The published clinical report on the “Comparative study of Professional vs Mass Market Topical Products for Treatment of Facial Photodamage” was release January 2016. The authors included two Zel Skin & Laser Specialists professionals, Irmina Wallander and Brian Zelickson.
Many over the counter topical products claim to reverse the signs of cutaneous photo-damage. To date, the two most studied ingredients for improving the texture, tone, and pigmentation of the skin are topical retinoids and hydroquinone.1
This split face study compares a mass market skincare regimen with a prescription skincare regimen for photo damaged skin.
Twenty-seven subjects with moderate facial photodamage enrolled. Each subject was consented and assigned with the mass market anti-aging system (Treatment A) to one side of the face. The prescription anti-aging system (Treatment B or Treatment C) was applied to the other side of the face. Treatment B contained 13 subjects whom did not use 0.025% Retinol cream. Treatment C contained 14 subjects who used a 0.025% Retinol Cream. Subjects had 4 visits over 12 weeks for digital photography and surveys. Blinded physicians evaluated the photographs.
Physician objective analysis showed all three systems to have a statistically significant clinical improvement in photoaged skin seen in as little as 4 weeks of use. Participant’s surveys rated the mass market system higher than both of the professional systems for visible skin changes, ease of use, and likelihood to recommend to a friend. Twelve of twenty-seven subjects preferred the mass market system for overall improvement while twelve thought each system gave the same improvement.
This study demonstrates a mass marketed system can give similar improvements as a professionally dispensed prescription system. The majority of participants preferred the mass-marketed system.
Authors: Hilary Reich MD,a,b Irmina Wallander BA,a Lacie Schulte MS BA,a Molly Goodier BS,a and Brian Zelickson MDa
aZel Skin & Laser Specialist, Edina, MN
bUniversity of Minnesota Department of Dermatology, MN